Nature Medicine
10, 1193 - 1199 (2004)
Published online: 10 October 2004; | doi:10.1038/nm1118
Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscleTakahiro Iwamoto, Satomi Kita, Jin Zhang, Mordecai P Blaustein, Yuji Arai, Shigeru Yoshida, Koji Wakimoto, Issei Komuro
& Takeshi KatsuragiSupplementary Fig. 1 (pdf 233K)
Expression levels and NCX activities in CCL39 fibroblasts overexpressing human NCX1 isoforms. Supplementary Fig. 2 (pdf 634K)
Effect of SEA0400 on the development of DOCA-salt hypertension in rats. Supplementary Fig. 3 (pdf 234K)
VSM-specific overexpression of NCX1.3 and its mutant in N1.3
Tg/Tg and N1.3
Tg/Tg mice. Supplementary Fig. 4 (pdf 303K)
Salt-insensitivity in transgenic mice with heart-specific overexpression of NCX1.1. Supplementary Table 1 (pdf 11)
Effects of SEA0400 on morphological changes of thoracic aortas in DOCA-salt hypertensive rats Supplementary Table 2 (pdf 11)
Effects of SEA0400 on creatinine clearance, urinary excretion of protein, and fractional excretion of sodium in DOCA-salt hypertensive rats Supplementary Movie (mov 2981)
Effects of ouabain and SEA0400 on cytosolic Ca2+ and myogenic tone in a small mesenteric artery. Supplementary Methods (pdf 24K)
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