Transplantation tolerance: babies take the first step
Jagdeep S Obhrai
& Fadi G Lakkis
The authors are in the Section of Nephrology (Department of Internal Medicine) and the Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06511, USA. fadi.lakkis@yale.edu or jagdeep.obhrai@yale.edu
Babies will accept transplants from donors of different blood groups, a situation that is catastrophic in adults. The basis for this acceptance is now examined and found to hinge on B-cell tolerance (pages 1227−1233).
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