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News and Views
Nature Medicine  10, 1161 - 1162 (2004)
doi:10.1038/nm1104-1161

Can nicotine treat sepsis?

Michael A Matthay1 & Lorraine B Ware2

1  Michael A. Matthay is at the Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California 94143-0130, USA. mmatt@itsa.ucsf.edu

2  Lorraine B. Ware is in the Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2650, USA.

The acetylcholine receptor modulates interactions between the nervous system and the immune system. An acetylcholine receptor agonist, nicotine, is now harnessed to dampen inflammation and reduce mortality in a mouse model of sepsis (pages 1216−1221).

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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