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Nature Medicine  10, 1049 - 1050 (2004)
doi:10.1038/nm1004-1049

Nutrient sensor links obesity with diabetes risk

Mary-Elizabeth Patti1 & Barbara B Kahn2

1  Mary-Elizabeth Patti is in the Research Division, Joslin Diabetes Center, Boston, Massachusetts 02215, USA and Harvard Medical School, Boston, Massachusetts 02215, USA. mary.elizabeth.patti@joslin.harvard.edu

2  Barbara B. Kahn is in the Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA and Harvard Medical School, Boston, Massachusetts 02215, USA. bkahn@bidmc.harvard.edu

Overeating can lead to the development of insulin resistance and diabetes. A component of the mTOR nutrient signaling pathway now bridges the mechanistic gap between obesity and insulin resistance.

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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