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Correspondence


Nature Medicine 10, 13 (2004)
doi:10.1038/nm0104-13

Reply to "FasL, leukocytes and vascular modeling"

Susumu Ishida1,2, Kenji Yamashiro1,3, Tomohiko Usui1,4 & Anthony P Adamis5

  1. Angiogenesis Laboratory/Retina Research Laboratory Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.
  2. Department of Ophthalmology, Keio University School of Medicine, Japan.
  3. Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Japan.
  4. Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Japan.
  5. Eyetech Research Center, Eyetech Pharmaceuticals, Woburn, Massachusetts 01801, USA.

We thank Ferguson and Stuart for their comments and appreciate the opportunity to respond. Our data show that leukocytes mediate physiological retinal vascular pruning and pathological vaso-obliteration.

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