Nature Medicine
1, 742 - 744 (1995)
doi:10.1038/nm0895-742
Genomic prospectingStephen J. O'BrienLaboratory of Viral Carcinogenesis, National Cancer Institute, Frederick, Maryland 21702, USA The importahce of preserving biodiversity extends beyond the discovery of new drugs to understanding how other species have dealt with medical problems we currently face.
REFERENCES
- Roberts, L. Chemical prospecting: Hope for vanishing ecosystems. Science 256, 1142−1143 (1992). | PubMed | ISI | ChemPort |
- Flam, F. Chemical prospectors scour the seas for promising drugs. Science 266, 1324−1325 (1994). | PubMed | ISI | ChemPort |
- O'Brien, S.J. A role for molecular genetics in biological conservation. Proc. natn. Acad. Sci. U.S.A. 91, 5748−5755 (1994). | ChemPort |
- O'Brien, S.J. Genetic and phylogenetic analyses of endangered species. Annu. Rev. Genet. 28, 467−489 (1994). | Article | PubMed | ChemPort |
- Trowsdale, J. Genomic structure and function in the MHC. Trends Genet. 9, 117−122 (1993). | Article | PubMed | ISI | ChemPort |
- O'Brien, S.J. et al. Genetic basis for species vulnerability in the cheetah. Science 227, 1428−1434 (1985). | PubMed | ChemPort |
- Heeney, J.L. et al. Prevalence and implications of feline coronavirus infections of captive and free-ranging cheetahs (Acinonyx jubatus). J. Virol. 64, 1964−1972 (1990). | PubMed | ISI | ChemPort |
- Black, F.L. Why did they die? Science 258, 1739−1740 (1992). | PubMed | ISI | ChemPort |
- Roelke, M.E., Martenson, J.S. & O'Brien, S.J. The consequences of demographic reduction and genetic depletion in the endangered Florida panther. Curr. Biol. 3, 340−350 (1993). | ISI |
- Gardner, M.B., Kozak, C. & O'Brien, S.J., Casitas wild mouse: Evolving genetic resistance to retroviral disease. Trends Genet. 7, 22−27 (1991). | Article | PubMed | ISI | ChemPort |
- Benveniste, R. The contributions of retroviruses to the study of mammalian evolution. In Molecular Evolutionary Genetics (ed. Maclntyre, RJ.) 3590−417 (Plenum, New York, 1985).
- Wilkinson, D.A., Mager, D.L. & Leony, J.C. Endogenous human retroviruses. in The Retroviridae (ed. Levy, J.A.) 465−535 (Plenum, New York, 1994). | ChemPort |
- Desrosiers, R.C. The simian immunodeficiency viruses. Annu. Rev. Immunol. 8, 557−578, 1990. | Article | PubMed | ISI | ChemPort |
- Hirsch, V.M. & Johnson, P.R. Pathogenic diversity of simian immunodeficiency viruses. Virus Res. 32, 183−203, 1994. | Article | PubMed | ISI | ChemPort |
- Pedersen, N.C., Ho, E.W., Brown, M.L. & Yamamoto, J.K. Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome. Science 235, 790−793, 1987. | PubMed | ISI | ChemPort |
- Olmsted, R.A. et al. Worldwide prevalence of lentivirus infection in wild feline species: Epidemiologic and phylogenetic aspects. J. Virol. 66, 6008−6018 (1992). | PubMed | ISI | ChemPort |
- Brown, E.W., Yuhki, N., Packer, C. & O'Brien, S.J. A lion lentivirus related to feline immunodeficiency virus: Epidemiologic and phylogenetic aspects. J. Virol. 68, 5953−5968 (1995). | ISI |
- O'Brien, S.J. et al. Anchored reference loci for comparative genome mapping in mammals. Nature Genet. 3, 103−112 (1993). | PubMed | ChemPort |
- Baltimore, D. Intracellular immunization. Nature 335, 395−396 (1988). | Article | PubMed | ISI | ChemPort |
|
