Nature Medicine
1, 481 - 483 (1995)
doi:10.1038/nm0595-481
Gene gun and other non-viral approaches for cancer gene therapyNing-Sun Yang1, 3
& Wenn H. Sun2
1Department Cancer Gene Therapy, Agracetus Inc., 8520 University Green, Middleton, Wisconsin 53562, USA, and
2Division of Dermatology, Children's Memorial Hospital, Lurie Cancer Center at Northwestern University, 2300 Children's Plaza/107, Chicago, Illinois 60614
3Correspondence should be addressed to N.−S.Y REFERENCES
- Kerr, W.G. & Mule, J.J. Gene therapy: Current status and future prospect. J. Leukocyte Biol. 56, 210−214 (1994). | PubMed | ISI | ChemPort |
- Culver, K.W., Blaese, R.M. Gene therapy for cancer. Trends Genet. 10, 174−178 (1994). | Article | PubMed | ISI | ChemPort |
- Foa, R. et al. Cytokine gene therapy: A new strategy for the management of cancer patients. Natural Immunity 13, 65−75 (1994). | PubMed | ISI | ChemPort |
- Nabel, G.J. et al. Immunotherapy for cancer by direct gene transfer into tumors. Hum. gene Ther. 5, 57−77 (1994). | PubMed | ISI | ChemPort |
- Hwu, P. & Rosenberg, S.A. The genetic modification of T cells for cancer therapy: An overview of laboratory and clinical trials. Cancer Detect. Prevent. 18, 43−50 (1994). | PubMed | ISI | ChemPort |
- Nabel, G.J. et al. A molecular genetic intervention for AIDS: Effects of a transdominant negative form of Rev. Hum. Gene Ther. 5, 79−92 (1994). | PubMed | ISI | ChemPort |
- Nabel, G.J. et al. Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biological activity, and lack of toxicity in humans. Proc. natn. Acad. Sci. U.S.A. 90, 11307−11311 (1993). | ChemPort |
- Sun, W.H. et al. In vivo cytokine gene transfer by gene gun reduces tumor growth in mice. Proc. natn. Acad. Sci. USA. 92, 2889−2893 (1995). | ChemPort |
- Woffendin, C. et al. Nonviral and viral delivery of a human immunodeficiency virus protective gene into primary human T cells. Proc. natn. Acad. Sci. U.S.A. 91, 11581−11585 (1994). | ChemPort |
- Tang, D.C., DeVit, M. & Johnston, S.A. Genetic immunization is a simple method for eliciting an immune response. Nature 356, 152−154 (1992). | Article | PubMed | ISI | ChemPort |
- Thompson, T.A. et al. Transient promoter activity in primary rat mammary epithelial cells evaluated using particle bombardment gene transfer. In vitro cell. dev. Biol. 29A, 165−170 (1993). | PubMed | ChemPort |
- Fynan, E.F. et al. DNA vaccines: Protective immunization by parenteral, mucosal, and gene-gun inoculation. Proc. natn. Acad. Sci. U.S.A. 90, 11478−11482 (1993). | ChemPort |
- Andree, C. et al. In vivo transfer and expression of a human epidermal growth factor gene accelerates wound repair. Proc. natn. Acad. Sci. U.S.A. 91, 12188−12192 (1994). | ChemPort |
- Yang, N.-S. et al. In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Proc. natn. Acad. Sci. U.S.A. 87, 9568−9572 (1990). | ChemPort |
- Yang, N.-S., Deluna, C. & Cheng, L. in Gene Therapeutics: Methods and Application of Direct Gene Transfer (ed. Wolff, J. A.) 193−209 (Birkhauser, Boston, 1994). | ChemPort |
- Yang, N.-S. in Particle Bombardment Technology for Gene Transfer (eds Yang, N.-S. & Christou, P.) 39−45 (Oxford University Press, Oxford, 1994).
- Yang, N.-S. & Ziegelhoffer, P. R. in The Particle Bombardment System for Mammalian Transfer (eds Yang, N.-S. & Christou, P.) 117-139 (Oxford University Press, Oxford, 1994). | ChemPort |
- Klein, I. et al. High-velocity microprojectiles for delivering nucleic acids into living cells. Nature 327, 70−73 (1987). | Article | ISI | ChemPort |
- Burkholder, J.K., Decker, J. & Yang, N.-S. Transgene expression in lymphocyte and macrophage primary cultures after particle bombardment. J. immunol. Meth. 165, 149−156 (1993). | Article | ISI | ChemPort |
- Rosenberg, S.A. et al. Prospective randomized trial of high-dose IL-2 alone or in conjunction with LAK cells for the treatment of patients with advanced cancer. J. natn. Cancer Inst. 85, 622−632 (1993). | Article | ChemPort |
- Dranoff, G. et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. natn. Acad. Sci. U.S.A. 90, 3539−3543 (1993). | ChemPort |
- Ogasawara, M. & Rosenberg, S.A. Enhanced expression of HLA molecules and stimulation of autologous human tumor infiltrating lymphocytes following transduction of melanoma cells with
-interferon genes. Cancer Res. 53, 3561−3568 (1993). | PubMed | ISI | ChemPort |
|