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Nature Medicine  1, 407 - 408 (1995)
doi:10.1038/nm0595-407

A 'senseless' immune response to DNA

Jeffrey T. Holt

Departments of Cell Biology and Pathology Vanderbilt University Medical School Nashville, Tennessee 37232, USA

Antisense oligonucleotides can have dramatic effects, but a recent paper suggests that the mechanism isn't always based on nucleotide sequence interactions.

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  8. Holt, J.T., Redner, R. & Nienhuis, A.W. An oligomer complementary to c-myc inhibits proliferation of HL60 promyelocytic Cells and induces differentiation. Molec Cell Biol. 8, 963−973 (1988). | PubMed  | ISI | ChemPort |
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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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