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Nature Medicine  1, 1141 - 1142 (1995)
doi:10.1038/nm1195-1141

gridlock: A model for coarctation of the aorta?

Jeffrey A. Towbin1 & Tim C. McQuinn2

  1Department of Pediatric Cardiology Baylor College of Medicine One Baylor Plaza, Room 333E Houston, Texas 77030, USA

  2Department of Pediatrics and Department of Anatomy and Cell Biology Medical University of South Carolina Charleston, South Carolina 29407, USA

A tiny fish may provide a big clue to an important cardiovascular malformation (pages 1143−1147).

REFERENCES
  1. Ho, S.Y. & Anderson, R.H. Coarctation, tubular hypoplasia, and the ductus arteriosus. Histological study of 35 specimens. Br. Heart J. 41, 268−274 (1979). | PubMed  | ChemPort |
  2. Morris, M.J.H. & McNamara, D.G. Coarctation of the aorta and interrupted aortic arch. in The Science and Practice of Pediatric Cardiology (eds Garson, A., Bricker, J.T. & McNamara, D.G.) 1353−1381 (Lea & Febiger, Malvern, Pennsylvania, 1990).
  3. Weinstein, B.M., Stemple, D.L., Driever, W. & Fishman, M.C. gridlock, a localized heritable vascular patterning defect in the zebrafish. Nature Med. 1, 1143−1147 (1995). | Article | PubMed  | ISI | ChemPort |
  4. Mullins, M.C., Hammerschmidt, M., Haffter, P. & Nusslein-Volhard, C. Large-scale mutagenesis in the zebrafish: In search of genes controlling development in a vertebrate. Curr. Biol. 4, 189−202 (1994). | PubMed  | ISI | ChemPort |
  5. Rossant, J. & Hopkins, H. Of fin and fur: Mutational analysis of vertebrate embryonic development. Genes Dev. 6, 1−13 (1992). | PubMed  | ISI | ChemPort |
  6. Fishman, M.C. & Stainier, D.Y. Cardiovascular development. Prospects for a genetic approach. Circ. Res. 74, 757−763 (1994). | PubMed  | ISI | ChemPort |
  7. Pardanoud, L., Altmann, C., Kitos, P., Dieterlen-Lievre, F. & Buck, C.A. Vasculogenesis in the early quail blastodisc as studied with a monoclonal antibody recognizing endothelial cells. Development 100, 339−349 (1987). | PubMed  | ISI | ChemPort |
  8. Peault, B., Coltey, M. & Le Douarin, N.M. Ontogenic emergence of a quail leukocyte/endothelium cell surface antigen. Cell Different. 23, 165−174 (1988). | Article | ISI | ChemPort |
  9. Coffin, J.D. & Poole, T.J. Endothelial cell origin and migration in embryonic heart and cranial blood vessel development. Anat. Rec. 231, 383−395 (1991). | PubMed  | ISI | ChemPort |
  10. Coffin, J.D., Harrison, J., Schwartz, S. & Heimark, R. Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo. Dev. Biol. 148, 51−62 (1991). | PubMed  | ISI | ChemPort |
  11. Clark, E.B. Mechanisms in the pathogenesis of congenital cardiac malformations. in Genetics of Cardiovascular Disease (eds Pierpont, M.E. & Moller, J.H.) (Martinus Nijhoff, 1986).
  12. Rudolph, A.M., Heymann, M.A. & Spitznas, U. Hemodynamic considerations in the development of narrowing of the aorta. Am. J. Cardiol. 30, 514−525 (1972). | Article | PubMed  | ISI | ChemPort |
  13. Hutchins, G.M. Coarctation of the aorta explained as a branch-point of the ductus arteriosus. Am. J. Path. 62, 203−207 (1971).
  14. Russell, G.A., Berry, P.J., Watterson, K., Dhasmana, J.P. & Wisheart, J.D. Patterns of ductal tissue in coarctation of the aorta in the first three months of life. J. thoracic cardiovasc. Surgery 102, 596−601 (1991). | ISI | ChemPort |
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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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