Focus


Focus on Inflammatory disease

There is an emerging understanding of how the disruption of immune homeostasis may lead to the development of chronic inflammatory diseases. This series of articles highlights new data that point toward the influence of environmental factors and addresses recent advances in our knowledge of the cell types and signaling pathways involved in inflammatory disease onset and progression.

Top

Editorial

Focus on Inflammatory disease

Big data meets mechanism

doi:10.1038/nm.3903


Top

News Feature

Focus on Inflammatory disease

A gut feeling about immunity

Roxanne Khamsi

doi:10.1038/nm.3906


Top

Reviews

Focus on Inflammatory disease

Influence of nutrient-derived metabolites on lymphocyte immunity

Marc Veldhoen & Cristina Ferreira

doi:10.1038/nm.3894


Focus on Inflammatory disease

Inflammasomes: mechanism of action, role in disease, and therapeutics

Haitao Guo, Justin B Callaway & Jenny P-Y Ting

doi:10.1038/nm.3893


Focus on Inflammatory disease

Innate lymphoid cells in the initiation, regulation and resolution of inflammation

Gregory F Sonnenberg & David Artis

doi:10.1038/nm.3892


Focus on Inflammatory disease

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

Michele W L Teng, Edward P Bowman, Joshua J McElwee, Mark J Smyth, Jean-Laurent Casanova, Andrea M Cooper & Daniel J Cua

doi:10.1038/nm.3895


Focus on Inflammatory disease

The emerging role of resident memory T cells in protective immunity and inflammatory disease

Chang Ook Park & Thomas S Kupper

doi:10.1038/nm.3883


Focus on Inflammatory disease

Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies

Judy Cho & Marc Feldman

doi:10.1038/nm.3897


Top