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Nature Immunology 9, 1011 - 1013 (2008)
doi:10.1038/ni0908-1011
The CD200-CD200R axis in local control of lung inflammation
Patrick G Holt1 & Deborah H Strickland1
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Patrick G. Holt and Deborah H. Strickland are with the Telethon Institute for Child Health Research and Centre for Child Health Research, Faculty of Medicine and Dentistry, The University of Western Australia, Nedlands 6009, Australia.
e-mail: patrick@ichr.uwa.edu.au
Abstract
Excessive lung inflammation in response to infection or allergens can lead to tissue damage and potentially loss of organ function. The CD200-CD200R interaction acts to limit such destructive immune responses in the lung.
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RESEARCH
A critical function for CD200 in lung immune homeostasis and the severity of influenza infectionNature Immunology Article (01 Sep 2008)
