News and Views
Nature Immunology 9, 1009 - 1011 (2008)
doi:10.1038/ni0908-1009
The making of NKT cells
Laurent Gapin1
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Laurent Gapin is in the Integrated Department of Immunology, University of Colorado Health Science Center and National Jewish Health, Denver, Colorado 80206, USA.
e-mail: gapinl@njc.org
Abstract
Natural killer T cells acquire their unique phenotype and characteristics during development in the thymus. Evidence suggests that the transcription factor PLZF has a unique function in the development of these cells and their acquisition of 'innate-like' characteristics.
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