About the cover
August 2008 Volume 9 No 8


CD8+ T cells mediate protection against the parasite Toxoplasma gondii. Shastri
and colleagues (p 937; News and Views by Jensen, p 829) identify an immunodominant T. gondii peptide whose production requires processing by the aminopeptidase ER AAP. The original image, generated by two-photon laser-scanning microscopy, shows a cyst containing T. gondii (red) surrounded by antigen-presenting cells (green) and T cells (blue) in the brain of an infected mouse. Original image by M. Schaeffer. Art work by Lewis Long.

