News and Views


Nature Immunology 9, 835 - 836 (2008)
doi:10.1038/ni0808-835

Arrestin NK cell cytotoxicity

Yenan T Bryceson1 & Hans-Gustaf Ljunggren2

  1. Yenan T. Bryceson is at the Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S-14186 Stockholm, Sweden and at the Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, USA.
    e-mail: yenan.bryceson@gmail.com
  2. Hans-Gustaf Ljunggren is at the Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S-14186 Stockholm, Sweden.
    e-mail: hans-gustaf.ljunggren@ki.se


A key regulator of the balance of signals that activate effector mechanisms versus those that restrain them, beta-arrestin 2 mediates the inhibition of natural killer cell cytotoxicity.

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