News and Views
Nature Immunology 9, 835 - 836 (2008)
doi:10.1038/ni0808-835
Arrestin NK cell cytotoxicity
Yenan T Bryceson1 & Hans-Gustaf Ljunggren2
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Yenan T. Bryceson is at the Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S-14186 Stockholm, Sweden and at the Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, USA.
e-mail: yenan.bryceson@gmail.com -
Hans-Gustaf Ljunggren is at the Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S-14186 Stockholm, Sweden.
e-mail: hans-gustaf.ljunggren@ki.se
Abstract
A key regulator of the balance of signals that activate effector mechanisms versus those that restrain them,
-arrestin 2 mediates the inhibition of natural killer cell cytotoxicity.
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