News and Views
Nature Immunology 9, 588 - 590 (2008)
doi:10.1038/ni0608-588
Differentiation of human TH-17 cells does require TGF-
!
Anne O'Garra1, Brigitta Stockinger1 & Marc Veldhoen1
- Anne O'Garra is in the Division of Immunoregulation and Brigitta Stockinger and Marc Veldhoen are in the Division of Molecular Immunology, Medical Research Council, National Institute for Medical Research, Mill Hill, London NW7 1AA, UK. e-mail: aogarra@nimr.mrc.ac.uk
Abstract
Three new studies demonstrate that development of human TH-17 cells requires transforming growth factor-
and one or more proinflammatory cytokines, which are the same requirements as for mouse TH-17 development.
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