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Nature Immunology 9, 345 - 346 (2008)
doi:10.1038/ni0408-345
New niches for B cells
Takashi Nagasawa1
- Takashi Nagasawa is in the Department of Immunobiology and Hematology, Institute for Frontier Medical Sciences, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. e-mail: tnagasa@frontier.kyoto-u.ac.jp
Abstract
The bone marrow contains specialized microenvironments that maintain blood cells and supply the requisite factors for their development. Newly identified bone marrow–resident dendritic cells create unique niches for mature B cells.
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RESEARCH
Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow nichesNature Immunology Article (01 Apr 2008)
