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March 2008 Volume 9 No 3

Lampreys express a diverse repertoire of variable lymphocyte receptors (VLRs). Cooper and colleagues (p 319) identify VLRB-producing cells that resemble mammalian B cells in the lamprey. A lamprey is shown in the foreground, and lamprey gill tissues immunostained for VLRB (green) and BrdU (red) are shown in the background; nuclei are stained with DAPI (blue). Artwork by Lewis Long.

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