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Nature Immunology 9, 231 - 233 (2008)
doi:10.1038/ni0308-231

Finally, MALT1 is a protease!

Linda M McAllister-Lucas1 & Peter C Lucas2

  1. Linda M. McAllister-Lucas is in the Division of Hematology and Oncology, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. e-mail: lindaluc@umich.edu
  2. Peter Lucas is in the Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA e-mail: plucas@umich.edu


Two groups demonstrate proteolytic activity for MALT1, a component of the signaling pathway mediating antigen receptor–dependent stimulation of the transcription factor NF-kappaB, and identify its first substrates.

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