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Nature Immunology 9, 124 - 126 (2008)
doi:10.1038/ni0208-124
IL-17 drives germinal center B cells?
David Tarlinton1
- David Tarlinton is in the Immunology Division, The Walter and Eliza Hall Institute for Medical Research, Parkville 3050, Australia. e-mail: tarlinton@wehi.edu.au
Abstract
The inflammatory cytokine interleukin 17, normally considered a T cell–associated factor, is now reported to be the central participant driving the development of germinal center–derived autoantibodies in a model disease setting.
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Interleukin 17?producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 miceNature Immunology Article (01 Feb 2008)
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