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Nature Immunology 9, 122 - 124 (2008)
doi:10.1038/ni0208-122
CD160 and BTLA: LIGHTs out for CD4+ T cells
Jonathan Kaye1
- Jonathan Kaye is in the Department of Immunology, IMM-4, The Scripps Research Institute, La Jolla, California 92037, USA. e-mail: jkaye@scripps.edu
Abstract
The T cell costimulatory protein LIGHT and coinhbitory protein BTLA share a common ligand, HVEM. Now CD160 is also shown to bind HVEM and deliver a potent inhibitory signal to CD4 T cells.
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