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Nature Immunology 9, 1327–1328 (1 December 2008) | doi:10.1038/ni1208-1327
RIG-I-like antiviral protein in flies
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Abstract
The immune system senses invasion by viruses and mounts antiviral responses for eliminating the infection using pattern-recognition receptors that discriminate self and viral components. In contrast to mammals, in which the type I interferon system is essential for antiviral immunity, insects such as Drosophila melanogaster do not encode a counterpart to type I interferon in their genome.
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