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Nature Immunology 9, 1329 - 1330 (2008)
doi:10.1038/ni1208-1329

Nervous about immunity: neuronal signals control innate immune system

Cheng-Yuan Kao1, Ferdinand C O Los1 & Raffi V Aroian1

  1. Cheng-Yuan Kao, Ferdinand C.O. Los and Raffi V. Aroian are in the Section of Cell and Developmental Biology, University of California, San Diego La Jolla, California 92093, USA.
    e-mail: raroian@ucsd.edu


The molecular mechanisms by which the nervous system influences innate immunity to pathogens remain mysterious. Two new studies show that neuronal products modulate established innate immune signaling pathways operative in the Caenorhabditis elegans intestine.

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