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Nature Immunology 9, 1327 - 1328 (2008)
doi:10.1038/ni1208-1327
RIG-I-like antiviral protein in flies
Osamu Takeuchi1 & Shizuo Akira1
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Osamu Takeuchi and Shizuo Akira are in the Department of Host Defense, World Premier International Immunology Frontier Research Center, and the Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
e-mail: sakira@biken.osaka-u.ac.jp
Abstract
The function of gene expression in the response of drosophila to viral infection is poorly understood. A report now demonstrates that the helicase Dicer-2 controls antiviral gene expression in addition to RNA interference–mediated gene silencing.
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