News and Views
Nature Immunology 9, 1208 - 1210 (2008)
doi:10.1038/ni1108-1208
Activated pDCs: open to new antigen-presentation possibilities
Tineke van den Hoorn1 & Jacques Neefjes1
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Tineke van den Hoorn and Jacques Neefjes are with the Division of Tumor Biology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
e-mail: j.neefjes@nki.nl
Abstract
Major histocompatibility complex class II molecules present peptides to CD4+ T cells. New findings indicate that conventional and plasmacytoid dendritic cells handle these molecules differently after activation.
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