News and Views
Nature Immunology 9, 1101 - 1102 (2008)
doi:10.1038/ni1008-1101
Tuberculosis: unsealing the apoptotic envelope
Steven A Porcelli1 & William R Jacobs Jr2
- Steven A. Porcelli is in the Department of Microbiology and Immunology and the Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
-
William R. Jacobs, Jr. is in the Department of Microbiology and Immunology, the Department of Genetics and Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
e-mail: jacobs@aecom.yu.edu
Abstract
Mycobacterium tuberculosis grows in macrophages but escapes these cells by triggering their death. New findings delineate how this pathogen controls macrophage death to favor bacterial survival and avoid host immunity.
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