News and Views


Nature Immunology 9, 1099 - 1100 (2008)
doi:10.1038/ni1008-1099

Sensing necrosis with Mincle

Gordon D Brown1

  1. Gordon D. Brown is with the Institute of Infectious Disease and Molecular Medicine, Clinical Laboratory Sciences, Division of Immunology, University of Cape Town, Observatory 7925, Cape Town, South Africa.
    e-mail: gordon.brown@mweb.co.za


The mechanisms that lead to inflammation after necrotic cell death are poorly understood. New data show that the C-type lectin Mincle is involved in this process.

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