Commentary abstract
Nature Immunology 9, 1091 - 1094 (2008)
doi:10.1038/ni1008-1091
The Immunological Genome Project: networks of gene expression in immune cells
Tracy S P Heng12, Michio W Painter12, The Immunological Genome Project Consortium, Kutlu Elpek1, Veronika Lukacs-Kornek1, Nora Mauermann1, Shannon J Turley1,11, Daphne Koller2,11, Francis S Kim3, Amy J Wagers4,4, Natasha Asinovski4, Scott Davis4, Marlys Fassett4, Markus Feuerer4, Daniel H D Gray4, Sokol Haxhinasto4, Jonathan A Hill4, Gordon Hyatt4, Catherine Laplace4, Kristen Leatherbee4, Diane Mathis4,11, Christophe Benoist4,11, Radu Jianu5, David H Laidlaw5,11, J Adam Best6, Jamie Knell6, Ananda W Goldrath6,11, Jessica Jarjoura7, Joseph C Sun7, Yanan Zhu7, Lewis L Lanier7,11, Ayla Ergun8, Zheng Li8, James J Collins8,11, Susan A Shinton9, Richard R Hardy9,11, Randall Friedline10, Katelyn Sylvia10 & Joonsoo Kang10,11
- Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.
- Department of Computer Science, Stanford University, Stanford, California 94305, USA.
- Section on Developmental and Stem Cell Biology, Joslin Diabetes Center, Boston, Massachusetts 02115, USA, and Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, Massachusetts 02138, USA.
- Section on Immunology and Immunogenetics, Joslin Diabetes Center, and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
- Department of Computer Science, Brown University, Providence, Rhode Island 02912, USA.
- Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093, USA.
- Department of Microbiology & Immunology and the Cancer Research Institute, University of California, San Francisco, San Francisco, California 94143, USA.
- Department of Biomechanical Engineering and Center for BioDynamics, Boston University, Boston, Massachusetts 02215, USA.
- Division of Basic Science, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
- Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.
- Principal investigator.
-
Tracy S.P. Heng and Michio W. Painter are in the Section on Immunology and Immunogenetics, Joslin Diabetes Center & Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.
e-mail: immgen@joslin.harvard.edu
Abstract
The Immunological Genome Project combines immunology and computational biology laboratories in an effort to establish a complete 'road map' of gene-expression and regulatory networks in all immune cells
