News and Views
Nature Immunology 8, 905 - 907 (2007)
doi:10.1038/ni0907-905
Regula'ten' the gut
- Paulo Vieira is with the Institut National de la Santé et de la Recherche Médicale U668 and Unité du Développement des Lymphocytes, Institut Pasteur, 75724 Paris Cedex 15, France.
- Anne O'Garra is in the Division of Immunoregulation, The National Institute for Medical Research, London NW7 1AA, UK. e-mail: aogarra@nimr.mrc.ac.uk
Abstract
Studies of genetically modified reporter mice have provided insight into the development of regulatory T cells. New work shows that regulatory T cells producing interleukin 10 arise in the periphery from Foxp3+ and Foxp3- thymic progenitors.
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