Table of contents


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Editorial

A hornet's nest for $1,000 p781

doi:10.1038/ni0807-781


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Commentary

Epitope-specific regulation: the elephant in the bathtub pp783 - 786

Leonore A Herzenberg

doi:10.1038/ni0807-783


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Meeting Report

Antigen receptor signaling: the Tuscan connection pp787 - 790

Cosima T Baldari & Gary A Koretzky

doi:10.1038/ni0807-787


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News and Views

Arresting autoimmunity by blocking beta-arrestin 1 pp791 - 792

Terra J Frederick & Stephen D Miller

doi:10.1038/ni0807-791

See also: Article by Shi et al.


Construction and destruction of MHC class I in the peptide-loading complex pp793 - 794

Gianna E Hammer & Nilabh Shastri

doi:10.1038/ni0807-793

See also: Article by Kienast et al. | Article by Wearsch & Cresswell


SWI-SNF: promoter of accessibility pp795 - 796

Andrea L Bredemeyer & Barry P Sleckman

doi:10.1038/ni0807-795

See also: Article by Osipovich et al.


No DL1 Notch ligand? GATA be a mast cell pp796 - 797

Susan Winandy & Melissa Brown

doi:10.1038/ni0807-796

See also: Article by Taghon et al.


Research Highlights p799

doi:10.1038/ni0807-799


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Review

Antigen receptor diversification and chromosome translocations pp801 - 808

Mila Jankovic, André Nussenzweig & Michel C Nussenzweig

doi:10.1038/ni1498


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Articles


Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1 pp817 - 824

Yufeng Shi, Yan Feng, Jiuhong Kang, Chang Liu, Zhenxin Li, Dangsheng Li, Wei Cao, Ju Qiu, Zhengliang Guo, Enguang Bi, Lei Zang, Chuanzhen Lu, Jingwu Z Zhang & Gang Pei

doi:10.1038/ni1489

See also: News and Views by Frederick & Miller


Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death pp825 - 834

Marta A Toscano, Germán A Bianco, Juan M Ilarregui, Diego O Croci, Jorge Correale, Joseph D Hernandez, Norberto W Zwirner, Francoise Poirier, Eleanor M Riley, Linda G Baum & Gabriel A Rabinovich

doi:10.1038/ni1482


Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes pp835 - 844

Dimitris Skokos, Guy Shakhar, Rajat Varma, Janelle C Waite, Thomas O Cameron, Randall L Lindquist, Tanja Schwickert, Michel C Nussenzweig & Michael L Dustin

doi:10.1038/ni1490



Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 pp856 - 863

Nicholas D Huntington, Hamsa Puthalakath, Priscilla Gunn, Edwina Naik, Ewa M Michalak, Mark J Smyth, Hyacinth Tabarias, Mariapia A Degli-Esposti, Grant Dewson, Simon N Willis, Noboru Motoyama, David C S Huang, Stephen L Nutt, David M Tarlinton & Andreas Strasser

doi:10.1038/ni1487




P-selectin primes leukocyte integrin activation during inflammation pp882 - 892

Hai-Bo Wang, Jin-Tao Wang, Lei Zhang, Zhen H Geng, Wei-Li Xu, Tao Xu, Yuqing Huo, Xueliang Zhu, Edward F Plow, Ming Chen & Jian-Guo Geng

doi:10.1038/ni1491


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Erratum

Erratum: Epigenetic regulation of Ifng expression p893

Charalampos G Spilianakis & Richard A Flavell

doi:10.1038/ni0807-893a


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Corrigendum

Corrigendum: Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-bold gamma p893

Jamie R Schoenborn, Michael O Dorschner, Masayuki Sekimata, Deanna M Santer, Maria Shnyreva, David R Fitzpatrick, John A Stamatoyonnapoulos & Christopher B Wilson

doi:10.1038/ni0807-893b


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