Supplementary information

From the following article

Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication

Ashleigh Hodges, Katherine Sharrocks, Mariola Edelmann, Dilair Baban, Arnaud Moris, Olivier Schwartz, Hal Drakesmith, Kay Davies, Benedikt Kessler, Andrew McMichael & Alison Simmons

Nature Immunology 8, 569 - 577 (2007) Published online: 13 May 2007

doi:10.1038/ni1470

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Supplementary Fig. 1

Panel of DC-SIGN antibodies tested for signaling but showing undetectable changes following western blot with anti-phosphotyrosine or anti-phosphoserine.

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Supplementary Fig. 2

Thp-1 DC-SIGN transfectants THP-1 + LL/AA and THP-1 + WT tested for signaling induced by H-200 prior to blocking with IB10 non-signaling anti-DC-SIGN.

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Supplementary Table 1

DC-SIGN transcriptional program: selected genes differentially regulated.

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Supplementary Table 2

Summary of differentially phosphorylated proteins.

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Supplementary Table 3

Proteins exclusively phosphorylated following DC-SIGN activation.

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