Supplementary information
From the following article
Takashi Tanaka, Michael J Grusby & Tsuneyasu Kaisho
Nature Immunology 8, 584 - 591 (2007) Published online: 29 April 2007
doi:10.1038/ni1464
Supplementary Fig. 1
Interaction of PDLIM2 mutants lacking LIM or PDZ domains with endogenous p65 is comparable to that of wild-type PDLIM2.
Supplementary Fig. 2
PDZ domain of PDLIM2 is not required for p65 ubiquitination.
Supplementary Fig. 3
Enhanced proinflammatory cytokine production in Pdlim2-/- cells in the absence of IFN-
.
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B activation by intranuclear sequestration and degradation of the p65 subunit