News and Views
Nature Immunology 8, 549 - 551 (2007)
doi:10.1038/ni0607-549
Antifungal defense turns 17
Noah W Palm1 & Ruslan Medzhitov1
- Noah W. Palm and Ruslan Medzhitov are with the Howard Hughes Medical Institute and Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06405, USA. e-mail: ruslan.medzhitov@yale.edu
Abstract
Fungal recognition occurs partially through the C-type lectin dectin-1. New studies show that dectin-mediated immune recognition of Candida albicans induces the differentiation of interleukin 17–producing T helper cells that express chemokine receptors characteristic of mucosal homing.
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