1. Noah W. Palm and Ruslan Medzhitov are with the Howard Hughes Medical Institute and Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06405, USA. e-mail: ruslan.medzhitov@yale.edu

Abstract

Fungal recognition occurs partially through the C-type lectin dectin-1. New studies show that dectin-mediated immune recognition of Candida albicans induces the differentiation of interleukin 17–producing T helper cells that express chemokine receptors characteristic of mucosal homing.

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