News and Views
Nature Immunology 8, 339 - 341 (2007)
doi:10.1038/ni0407-339
Rolling on N-linked glycans: a new way to present L-selectin binding sites
- Ronen Alon is in the Department of Immunology, Weizmann Institute of Science, Rehovot, 76100 Israel.
- Steven Rosen is in the Department of Anatomy and Program in Immunology, University of California, San Francisco, San Francisco, California, 94143-0451, USA.
Correspondence to: Ronen Alon1 e-mail: ronen.alon@weizmann.ac.il
Correspondence to: Steven Rosen2 e-mail: steven.rosen@ucsf.edu
Abstract
Recruitment of lymphocytes to the lymph nodes requires L-selectin-mediated recognition of carbohydrate determinants presented by O-glycans. New work shows that N-glycans 'decorated' with the same determinants also contribute to lymphocyte homing.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
A sulfated address for lymphocyte homingNature Immunology News and Views (01 Nov 2005)
Seeing cellular sialidase transform sugarsNature Chemical Biology News and Views (01 Dec 2008)
See all 6 matches for News And ViewsRESEARCH
The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial designNature Structural Biology Correspondence (01 Nov 1996)
Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitmentNature Immunology Article (01 Apr 2007)
See all 23 matches for Research
