News and Views
Nature Immunology 8, 337 - 339 (2007)
doi:10.1038/ni0407-337
Killing some to make way for others
Jeffrey V Ravetch1 & Michel Nussenzweig1
- Jeffrey V. Ravetch is in the Laboratory of Molecular Genetics and Immunology and Michel Nussenzweig is in the Laboratory of Molecular Immunology, Rockefeller University, New York, New York 10021, USA. e-mail: ravetch@mail.rockefeller.edu
Abstract
Limited niche availability restricts the number of long-lived plasma cells that can reside in the bone marrow. New research describes homeostatic regulatory mechanisms that allow newly 'minted' plasma cells to gain entry to such niches.
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