News and Views
Nature Immunology 8, 230 - 232 (2007)
doi:10.1038/ni0307-230
Local sentries for class switching
Michael McHeyzer-Williams1
- Michael McHeyzer-Williams is with The Scripps Research Institute, La Jolla, California 92037, USA. e-mail: mcheyzer@scripps.edu
Abstract
Epithelial cells responding to inflammatory stimuli can initiate class switching and antibody secretion in naive B cells. TSLP, BAFF and SLPI are epithelial cell–derived local regulators of effector B cell responses in mucosal environments.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPINature Immunology Article (01 Mar 2007)
Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioningMucosal Immunology Article Response
