News and Views


Nature Immunology 8, 122 - 124 (2007)
doi:10.1038/ni0207-122

A pair of 9s: it's in the CARDs

David M Underhill1 & Takahiro Shimada1

  1. David M. Underhill and Takahiro Shimada are with the Immunobiology Research Institute, Cedars-Sinai Medical Center, and the Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California 90048, USA. e-mail: david.underhill@cshs.org


New work shows that CARD9, the recently identified member of the caspase recruitment domain–containing family, directly interacts with the cytoplasmic protein Nod2 in the detection of intracellular bacteria.

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