Table of contents


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Editorial

Global scourge p1267

doi:10.1038/ni1207-1267


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Essay

Bacterial cell walls, innate immunity and immunoadjuvants pp1269 - 1271

Jack L Strominger

doi:10.1038/ni1207-1269


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Commentaries

Science, medicine and research in the developing world: a perspective pp1273 - 1276

Frances Gotch & Jill Gilmour

doi:10.1038/ni1531


Global health science: a threat and an opportunity for collaborative clinical science pp1277 - 1279

Jeremy Farrar

doi:10.1038/ni1532


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News and Views


CCR5 and its ligands: a new axis of evil? pp1283 - 1285

Michael M Lederman & Scott F Sieg

doi:10.1038/ni1207-1283

See also: Article by Dolan et al.


Competition for cytokines: Treg cells take all pp1285 - 1287

Alexander Scheffold, Kenneth M Murphy & Thomas Höfer

doi:10.1038/ni1207-1285

See also: Article by Pandiyan et al.


Macrophage tolerance: CD47–SIRP-alpha–mediated signals matter pp1287 - 1289

Hitoshi Takizawa & Markus G Manz

doi:10.1038/ni1207-1287

See also: Article by Takenaka et al.


Unexpected partnership between IL-15 and DAP10 pp1289 - 1291

Francesco Colucci

doi:10.1038/ni1207-1289

See also: Article by Horng et al.


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Research Highlights

Research Highlights p1293

doi:10.1038/ni1207-1293


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Articles

'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage pp1303 - 1312

Nicole C Kaneider, Andrew J Leger, Anika Agarwal, Nga Nguyen, George Perides, Claudia Derian, Lidija Covic & Athan Kuliopulos

doi:10.1038/ni1525


Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells pp1313 - 1323

Katsuto Takenaka, Tatiana K Prasolava, Jean C Y Wang, Steven M Mortin-Toth, Sam Khalouei, Olga I Gan, John E Dick & Jayne S Danska

doi:10.1038/ni1527

See also: News and Views by Takizawa & Manz


CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms pp1324 - 1336

Matthew J Dolan, Hemant Kulkarni, Jose F Camargo, Weijing He, Alison Smith, Juan-Manuel Anaya, Toshiyuki Miura, Frederick M Hecht, Manju Mamtani, Florencia Pereyra, Vincent Marconi, Andrea Mangano, Luisa Sen, Rosa Bologna, Robert A Clark, Stephanie A Anderson, Judith Delmar, Robert J O'Connell, Andrew Lloyd, Jeffrey Martin, Seema S Ahuja, Brian K Agan, Bruce D Walker, Steven G Deeks & Sunil K Ahuja

doi:10.1038/ni1521

See also: News and Views by Lederman & Sieg


Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor pp1337 - 1344

Thierry Walzer, Laura Chiossone, Julie Chaix, Andrew Calver, Claude Carozzo, Laure Garrigue-Antar, Yannick Jacques, Myriam Baratin, Elena Tomasello & Eric Vivier

doi:10.1038/ni1523




Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10 pp1363 - 1371

Jason S Stumhofer, Jonathan S Silver, Arian Laurence, Paige M Porrett, Tajie H Harris, Laurence A Turka, Matthias Ernst, Christiaan J M Saris, John J O'Shea & Christopher A Hunter

doi:10.1038/ni1537

See also: News and Views by Jankovic & Trinchieri | Article by Fitzgerald et al. | Article by Awasthi et al. | Article by McGeachy et al.





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Erratum

Erratum: Immune responses to commensal and environmental microbes p1398

Eric G Pamer

doi:10.1038/ni1207-1398a


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Corrigendum

Corrigendum: Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-bold gamma p1398

Jamie R Schoenborn, Michael O Dorschner, Masayuki Sekimata, Deanna M Santer, Maria Shnyreva, David R Fitzpatrick, John A Stamatoyannopoulos & Christopher B Wilson

doi:10.1038/ni1207-1398b


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