Focus on Pathogenesis

Pathogenesis: how far have we come? - p1141

doi:10.1038/ni1107-1141

Full Text - Pathogenesis: how far have we come? | PDF (153 KB) - Pathogenesis: how far have we come?

Focus on Pathogenesis

In vivo veritas: pathogenesis of infection as it actually happens - pp1143 - 1147

Herbert W 'Skip' Virgin

doi:10.1038/ni1529

Abstract - In vivo: veritas: pathogenesis of infection as it actually happens | Full Text - In vivo veritas: pathogenesis of infection as it actually happens | PDF (1,019 KB) - In vivo veritas: pathogenesis of infection as it actually happens

Focus on Pathogenesis

From influenza to HIV—and back? - pp1149 - 1151

Andrew J McMichael

doi:10.1038/ni1107-1149

Full Text - From influenza to HIV—and back? | PDF (304 KB) - From influenza to HIV—and back?

Focus on Pathogenesis

Dynamics of host defense: the view at the front lines - pp1153 - 1157

Peter Velázquez, Janelle C Waite & Michael L Dustin

doi:10.1038/ni1520

Full Text - Dynamics of host defense: the view at the front lines | PDF (641 KB) - Dynamics of host defense: the view at the front lines

Focus on Pathogenesis

Immunopathology of highly virulent pathogens: insights from Ebola virus - pp1159 - 1164

Carisa A Zampieri, Nancy J Sullivan & Gary J Nabel

doi:10.1038/ni1519

Abstract - Immunopathology of highly virulent pathogens: insights from Ebola virus | Full Text - Immunopathology of highly virulent pathogens: insights from Ebola virus | PDF (1,180 KB) - Immunopathology of highly virulent pathogens: insights from Ebola virus

Focus on Pathogenesis

Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases - pp1165 - 1171

Lluis Quintana-Murci, Alexandre Alcaïs, Laurent Abel & Jean-Laurent Casanova

doi:10.1038/ni1535

Abstract - Immunology : in natura: : clinical, epidemiological and evolutionary genetics of infectious diseases | Full Text - Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases | PDF (901 KB) - Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases

Focus on Pathogenesis

Immune responses to commensal and environmental microbes - pp1173 - 1178

Eric G Pamer

doi:10.1038/ni1526

Abstract - Immune responses to commensal and environmental microbes | Full Text - Immune responses to commensal and environmental microbes | PDF (653 KB) - Immune responses to commensal and environmental microbes

Focus on Pathogenesis

Pathogen subversion of cell-intrinsic innate immunity - pp1179 - 1187

Craig R Roy & Edward S Mocarski

doi:10.1038/ni1528

Abstract - Pathogen subversion of cell-intrinsic innate immunity | Full Text - Pathogen subversion of cell-intrinsic innate immunity | PDF (674 KB) - Pathogen subversion of cell-intrinsic innate immunity

Focus on Pathogenesis

Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic - pp1188 - 1193

Rafi Ahmed, Michael B A Oldstone & Peter Palese

doi:10.1038/ni1530

Abstract - Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic | Full Text - Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic | PDF (559 KB) - Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic

Focus on Pathogenesis

Research Highlights - p1195

doi:10.1038/ni1107-1195

Full Text - Research Highlights | PDF (74 KB) - Research Highlights

Rsk Tolls the bell for endocytosis in DCs - pp1197 - 1199

Michael Karin

doi:10.1038/ni1107-1197

Full Text - Rsk Tolls the bell for endocytosis in DCs | PDF (319 KB) - Rsk Tolls the bell for endocytosis in DCs

See also: Article by Zaru et al.

Dendritic cell genealogy: a new stem or just another branch? - pp1199 - 1201

Miriam Merad & Florent Ginhoux

doi:10.1038/ni1107-1199

Full Text - Dendritic cell genealogy: a new stem or just another branch? | PDF (656 KB) - Dendritic cell genealogy: a new stem or just another branch?

See also: Article by Onai et al. | Article by Naik et al.

Inhibitory receptors: whose side are they on? - pp1201 - 1203

Alison Crawford & E John Wherry

doi:10.1038/ni1107-1201

Full Text - Inhibitory receptors: whose side are they on? | PDF (271 KB) - Inhibitory receptors: whose side are they on?

See also: Article by Kaufmann et al.

Research Highlights - p1205

doi:10.1038/ni1107-1205

Full Text - Research Highlights | PDF (72 KB) - Research Highlights

Identification of clonogenic common Flt3⁺M-CSFR⁺ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow - pp1207 - 1216

Nobuyuki Onai, Aya Obata-Onai, Michael A Schmid, Toshiaki Ohteki, David Jarrossay & Markus G Manz

doi:10.1038/ni1518

Abstract - Identification of clonogenic common Flt3: +: M-CSFR: +: plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow | Full Text - Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow | PDF (755 KB) - Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow | Supplementary information

See also: News and Views by Merad & Ginhoux | Article by Naik et al.

Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo - pp1217 - 1226

Shalin H Naik, Priyanka Sathe, Hae-Young Park, Donald Metcalf, Anna I Proietto, Aleksander Dakic, Sebastian Carotta, Meredith O'Keeffe, Melanie Bahlo, Anthony Papenfuss, Jong-Young Kwak, Li Wu & Ken Shortman

doi:10.1038/ni1522

Abstract - Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived : in vitro: and : in vivo | Full Text - Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo | PDF (510 KB) - Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo | Supplementary information

See also: News and Views by Merad & Ginhoux | Article by Onai et al.

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways - pp1227 - 1235

Rossana Zaru, Natalia Ronkina, Matthias Gaestel, J Simon C Arthur & Colin Watts

doi:10.1038/ni1517

Abstract - The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways | Full Text - The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways | PDF (374 KB) - The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways | Supplementary information

See also: News and Views by Karin

COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor–induced entry into the cell cycle from quiescence - pp1236 - 1245

Suchithra Menon, Hongbo Chi, Huiyong Zhang, Xing Wang Deng, Richard A Flavell & Ning Wei

doi:10.1038/ni1514

Abstract - COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence | Full Text - COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor–induced entry into the cell cycle from quiescence | PDF (730 KB) - COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor–induced entry into the cell cycle from quiescence | Supplementary information

Upregulation of CTLA-4 by HIV-specific CD4⁺ T cells correlates with disease progression and defines a reversible immune dysfunction - pp1246 - 1254

Daniel E Kaufmann, Daniel G Kavanagh, Florencia Pereyra, John J Zaunders, Elizabeth W Mackey, Toshiyuki Miura, Sarah Palmer, Mark Brockman, Almas Rathod, Alicja Piechocka-Trocha, Brett Baker, Baogong Zhu, Sylvie Le Gall, Michael T Waring, Ryan Ahern, Kristin Moss, Anthony D Kelleher, John M Coffin, Gordon J Freeman, Eric S Rosenberg & Bruce D Walker

doi:10.1038/ni1515

Abstract - Upregulation of CTLA-4 by HIV-specific CD4: +: T cells correlates with disease progression and defines a reversible immune dysfunction | Full Text - Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction | PDF (1,128 KB) - Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction | Supplementary information

See also: News and Views by Crawford & Wherry

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells - pp1255 - 1265

Alexander Link, Tobias K Vogt, Stéphanie Favre, Mirjam R Britschgi, Hans Acha-Orbea, Boris Hinz, Jason G Cyster & Sanjiv A Luther

doi:10.1038/ni1513

Abstract - Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells | Full Text - Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells | PDF (772 KB) - Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells | Supplementary information

Corrigendum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes - p1266

Dimitris Skokos, Guy Shakhar, Rajat Varma, Janelle C Waite, Thomas O Cameron, Randall L Lindquist, Tanja Schwickert, Michel C Nussenzweig & Michael L Dustin

doi:10.1038/ni1107-1266a

Full Text - Corrigendum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes | PDF (63 KB) - Corrigendum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes

Corrigendum: Regulation of naive T cell function by the NF-B pathway - p1266

Naozumi Ishimaru, Hidehiro Kishimoto, Yoshio Hayashi & Jonathan Sprent

doi:10.1038/ni1107-1266b

Full Text - Corrigendum: Regulation of naive T cell function by the NF-B pathway | PDF (59 KB) - Corrigendum: Regulation of naive T cell function by the NF-B pathway

Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9 - p1266

Eicke Latz, Anjali Verma, Alberto Visintin, Mei Gong, Cherilyn M Sirois, Dionne C G Klein, Brian G Monks, C James McKnight, Marc S Lamphier, W Paul Duprex, Terje Espevik & Douglas T Golenbock

doi:10.1038/ni1107-1266c

Full Text - Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9 | PDF (59 KB) - Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9

Corrigendum: The clonal selection theory: 50 years since the revolution - p1266

Philip D Hodgkin, William R Heath & Alan G Baxter

doi:10.1038/ni1107-1266d

Full Text - Corrigendum: The clonal selection theory: 50 years since the revolution | PDF (59 KB) - Corrigendum: The clonal selection theory: 50 years since the revolution