News and Views
Nature Immunology 8, 1197 - 1199 (2007)
doi:10.1038/ni1107-1197
Rsk Tolls the bell for endocytosis in DCs
Michael Karin1
-
Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, Cancer Center, School of Medicine, University of California, San Diego, La Jolla, California 92093-0723, USA.
e-mail: karinoffice@ucsd.edu
Abstract
The mitogen-activated protein kinases Erk and p38 transduce Toll-like receptor signals that lead to antigen capture by dendritic cells. New work identifies 'downstream' effector kinases essential for these responses and traces a pathway of mitogen-activated protein kinase signaling apparently unique to dendritic cells.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathwaysNature Immunology Article (01 Nov 2007)
Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltrationInternational Journal of Obesity Original Article
