News and Views
Nature Immunology 8, 1031 - 1033 (2007)
doi:10.1038/ni1007-1031
Two in one: dual function of an invertebrate antigen receptor
Thomas Boehm1
- Thomas Boehm is in the Department of Developmental Immunology, Max-Planck Institute of Immunobiology, D-79108 Freiburg, Germany. e-mail: boehm@immunbio.mpg.de
Abstract
Differential splicing generates thousands of isoforms of the arthropod cell surface receptor Dscam. A new study explains the ability of these receptors to simultaneously generate homophilic and heterophilic interaction surfaces.
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