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Nature Immunology 8, 1029 - 1031 (2007)
doi:10.1038/ni1007-1029
Oxidative burst without phagocytes: the role of respiratory proteins
Christian Bogdan1
- Christian Bogdan, Institute of Clinical Microbiology, Immunology and Hygiene, University Clinic of Erlangen, D-91054 Erlangen, Germany. e-mail: christian.bogdan@uk-erlangen.de
Abstract
Respiratory proteins of vertebrates (hemoglobin) and invertebrates (hemocyanin) can generate highly reactive oxygen intermediates. New work shows that microbial compounds directly activate this release of reactive oxygen intermediates that kills the microbes.
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