Supplementary information

From the following article

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides

Gianna Elena Hammer, Federico Gonzalez, Edward James, Hector Nolla & Nilabh Shastri

Nature Immunology 8, 101 - 108 (2007) Published online: 26 November 2006

doi:10.1038/ni1409

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Supplementary Fig. 1

Model to explain the origin and immunogenicity of unedited, novel pMHC I expressed by ERAAP-deficient cells.

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Supplementary Fig. 2

The CD8+ T cell alloresponse to Kbm-1 MHC class I expressing cells is comparable to BEko T and ERAAP-deficient anti-WT CD8+ T cell responses.

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