Immune responses to microbial challenge in various tissues are not the same. Organ-specific immune responses are adapted to maintain organ physiology.
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Acknowledgements
I thank R. Seder (Vaccine Research Center, US National Institutes of Health), S. Datta and M. Corr (University of California San Diego) for their useful comments and L. Beck for editorial assistance. Supported by the National Institutes of Health (AI40682, AI57709 and HL79449).
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Raz, E. Organ-specific regulation of innate immunity. Nat Immunol 8, 3–4 (2007). https://doi.org/10.1038/ni0107-3
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DOI: https://doi.org/10.1038/ni0107-3
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