Nature Immunology 7, 798 - 800 (2006)
doi:10.1038/ni0806-798
IL-2 gets with the programStephen P Schoenberger
& Edith M Janssen
Stephen P. Schoenberger and Edith M. Janssen are in the Laboratory of Cellular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA. sps@liai.org
Many aspects of the CD8+ T lymphocyte response are 'programmed' by inductive stimuli during primary activation. A recent Nature paper shows that interleukin 2 signals endow CD8 T cells with the capacity for secondary population expansion during priming.
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