Nature Immunology 7, 791 - 792 (2006)
doi:10.1038/ni0806-791
Selection of intraepithelial   cells: the Holy GrIEL at last?Marc Bonneville
Marc Bonneville is with Institut National de la Santé et de la Recherche Médicale, U601, 44035 Nantes, France. bonnevil@nantes.inserm.fr
Although   T cells were discovered fortuitously more than 20 years ago, their development remains enigmatic. Genetic evidence now suggests that T lymphocytes undergo intrathymic positive selection.
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