Nature Immunology 7, 702 - 704 (2006)
doi:10.1038/ni0706-702
NK cell development: Gas mattersThierry Walzer
& Eric Vivier
Thierry Walzer and Eric Vivier are with the Centre d'Immunologie de Marseille-Luminy, Université de la Méditerranée, Case 906, 13288 Marseille cedex 9, France; Institut National de la Santé et de la Recherche Médicale, U631, 13288 Marseille, France; and Centre National de la Recherche Scientifique, UMR6102, 13288 Marseille, France. vivier@ciml.univ-mrs.fr
The mechanisms governing natural killer cell development are not well understood. Activation of the tyrosine kinase receptors Tyro3, Axl and Mer on pre–natural killer cells by stromal cell–produced ligands now seems to be critical.
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