Nature Immunology 7, 553 - 555 (2006)
doi:10.1038/ni0606-553
Stress management for T helper differentiationKenneth M Murphy
Kenneth M. Murphy is in the Department of Pathology and Immunology, Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis Missouri, 63110, USA. Murphy@immunology.wustl.edu
The integrated stress response is a complex signaling pathway that regulates myriad cell processes, including protein translation, depending on the stress conditions. Primed CD4+ T helper cells may use this response system to optimize cytokine expression.
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