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Nature Immunology 7, 549 - 551 (2006)
doi:10.1038/ni0606-549

Cytosolic detection of flagellin: a deadly twist

Craig R Roy & Dario S Zamboni

Craig R. Roy and Dario S. Zamboni are with the Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut 06536, USA. craig.roy@yale.edu

Immune responses to bacterial infection occur by host cell detection of bacterial components. Monomeric flagellin can be elicited directly by host cells and then are 'sensed' by the cytosolic protein Ipaf.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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