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Nature Immunology 7, 329 - 332 (2006)
doi:10.1038/ni0406-329

The sense of place in the immune system

Michael D Cahalan & George A Gutman

Supplementary Video 1 (avi 5.7M)
CD4+ T cell—dendritic cell interactions within the diffuse cortex of a lymph node approx10 hours into a priming immune response. Note stable contacts between several T cells (red) with individual dendritic cells (green) during this cluster stage of the interaction. Reproduced from The Journal of Experimental Medicine (ref. 25) by copyright permission of The Rockefeller University Press (www.jem.org).

Supplementary Video 2 (avi 1.9M)
Helper T cell—B cell conjugate pairs viewed 'waltzing' near the edge of a lymph node follicle approx30 hr after priming with antigen. Note rapid motility stable pairs, with B cells (red) leading T cells (green). Reproduced from PLoS Biology (ref. 26) with permission from the authors (www.plosbiology.org).


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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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