Release the hounds! A chemokine elicits monocytes from bone marrow
Barrett J Rollins
Barrett J. Rollins is in the Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts 02116, USA. barrett_rollins@dfci.harvard.edu
The chemokine receptor CCR2 was believed to 'summon' infiltrating CCR2+ monocytes into the spleen. Instead, CCR2 seems to be important for 'release' of these cells from bone marrow niches.
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